Name: Calming Chews
Brand: Wuffes
SKU: DCSC50
Availability: InStock

Made in the USA*
*from globally sourced ingredients
GMP Certified
In-Line with FDA CVM Guidelines
No By-Products
No Artificial Colors, Flavors or Preservatives
GMO, Hormone and Antibiotic-Free
No Seed Oils, Peas, Soy, Potatoes or Lentils
The 90-Day Promise
3rd Party Tested
NASC-Certified

50% of Dogs Suffer From Fear and Anxiety in The US*

And for the dog people watching it happen, it's exhausting and heartbreaking. The restlessness that won't settle. The triggers that come out of nowhere. The feeling that you'd do anything to help them, but nothing quite works.

These aren't behavior problems, they're signs your dog needs emotional balance support. That's what we built Calming Chews for – a supplement that works with the dog they already are.

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A close-up of a golden retriever's black nose and pale muzzle

*Source: Texas A&M College of Veterinary Medicine.

Benefits

Supports a calm, settled state – without leaving them drowsy, blank or not quite themselves.

Works with the brain's own calming system. Not switched off, just dialed down to where it should be.

Supports normal cortisol levels during everyday stress, so the stress response stays proportionate – not overwhelming, not suppressed. Just balanced.

For dogs that are still completely themselves – just calmer, steadier and more settled day to day.

A light-coated dog reclining on a grey pin-striped bed against a dark green headboard, relaxed and calm

More 5 star reviews than anyone else? That's us.

4.5

*Based on 5 star Trustpilot reviews among US dog supplement brands as of September 2026. Source: Trustpilot.

Results Timeline

Our supplements are built for the long game. The more consistent you are, the harder they work.

A tricolour spaniel stands beside a food bowl and a Wuffes jar on dry grass next to its seated owner

WEEK 1LAY THE GROUNDWORK

From the first chew, the ingredients are getting to work – supporting serotonin pathways and the nervous system's natural calming pathways. Nothing visible yet, that's normal. This is the stage where the real work begins, even if you can't see it.

A black-and-white spaniel sniffs among leafy garden plants on a bark-mulch path

WEEKS 2–3SOMETHING'S STARTING TO SHIFT

You might notice it before they can tell you. A moment that would usually set them off – the doorbell, a car journey, the trip to the vet – and they're a little more settled than before. Still them, just calmer. That's the natural chill starting to build.

A tricolour spaniel stands on a gravel farm track with its tongue out under a cloudy sky

WEEKS 4–6YOU'LL SEE IT. THEY'LL FEEL IT.

At this point you should notice less reactivity. Quicker recovery after stressful moments and a more stable mood day-to-day. This is where their new chilled side is starting to come out.

A tricolour spaniel lies on a patio beneath a garden chair while its owner reaches down to stroke it

WEEKS 6–8IN FULL FORCE

Calm, balanced behavior is now becoming the daily baseline. The dog that used to spin out at every trigger is finding their feet. Keep going, this is what the long game looks like.

Relora® is used under license.

Remember: Every dog is different. Size, age, where they're starting from – it all plays a part. Daily use is what makes the difference. These are supplements, not quick fixes.

Start before the stress hits

For everyday stress, take daily.
For the big moments – vet visits, fireworks, travel – start 3–4 weeks before.
Give it time to work.

A tricolour spaniel lies on a patio beside a Wuffes jar at its owner's feet, with blue water barrels behind

How we raise the bar

Calm, Not Sedated.

There's a difference between calm and drowsy. We want the first one.

Our Calming Chews are powered by a blend of gentle, but effective ingredients. Relora®, GABA, L-Tryptophan and Chamomile are formulated to promote real relaxation without the strong sedative effects.

No Spikes Around Here.

Dopamine is the rollercoaster. Serotonin is the cruise control. One spikes. One stays. Our Calming Chews are formulated with L-Tryptophan — a precursor to Serotonin — to support long-term, leveled-out calming effects.

Naturally Powered by Relora®.

Relora® is clinically validated to support your dog's normal cortisol response. Derived from the natural extract of Magnolia Bark and Phellodendron Bark that works with the brain's own stress regulation system.

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Relora® is used under license.

Real dogs. Real results.

The moment you notice your dog is back to themselves – we never get tired of hearing it.

A black pug with a greying muzzle sleeps nestled in white bedding

Calming Chews

7–9 years old

Pug

My picky pups enjoy these chews and do not turn their nose up at them! We take them at bedtime and it helps us have a calm sleep routine. Would recommend!

Norma P.

A tan dog sleeps curled up on a blue patterned dog bed on a wooden floor

Calming Chews

4–6 years old

Labrador Retriever

Our beautiful girl was previously abused. She was so skittish over the smallest noises. We have been giving them periodically to her. She's more relaxed.

Kim L.

A tan boxer mix walks towards the camera across a wood-effect floor, with other dogs behind and beside it

Calming Chews

While two of my dogs experience anxiety, all five of my dogs liked the taste and thought that they were treats! They were easy to break apart of needed for smaller dogs For my anxious dogs, it is a gentle, non-sedating calming support that definitely took the edge off. I noticed a difference in their behavior about two weeks into a daily dosage routine. Wuffes Calming Chews were much more effective other brands that I have tried in the past. I would definitely recommend them and continue my subscription!

Kasey K.

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TRUSTED BY OVER 1.3 MILLION DOG PEOPLE. You're in good company.

A customer in the driver's seat with her Australian Shepherd in the back of the car

Calming Chews

$35.95

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A customer sitting on a bed holding her small fluffy terrier mix

Calming Chews

$35.95

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A customer in her car with her black German Shepherd resting on the back seat

Calming Chews

$35.95

Try now

Calming Chews

$35.95

Try now

Calming Chews

$35.95

Try now

Calming Chews

$35.95

Try now

Calming Chews

$35.95

Try now

Calming Chews

$35.95

Try now

Calming Chews

$35.95

Try now

The Wuffes Standard™

Scientific principles we obsess over, because every milligram matters.

The right ingredients

Four clinically-tested actives, each targeting a different part of the stress response. Relora®, clinically validated to support the normal cortisol response, Chamomile for relaxation, GABA to support the nervous system's natural calming pathways and L-Tryptophan to support long-term serotonin production.
The right concentrations

With 390mg of actives per 2 chews. Formulated at concentrations meaningful enough to support a genuine calming response without tipping into sedation. Because the difference between calm and drowsy is often just a matter of how much.
The right blends

Each ingredient targets a specific area, but they work together to achieve the same goal; better stress support.
Relora® supports a normal cortisol response. While GABA (Gamma-Aminobutyric Acid), L-Tryptophan and Chamomile Extract work together to support healthy neurotransmitter activity, balance emotions and ease restlessness.
Relora® is used under license.

What's inside?

Clinically-tested ingredients picked for a purpose and crafted into a blend that makes use of every milligram.

Relora®

A piece of magnolia bark beside a pale phellodendron seed

Relora®

STRESS · CORTISOL RESPONSE

Helps support a normal stress response and balance emotions. A combination of two plant extracts – Magnolia Bark and Phellodendron Bark – Relora® works with the brain's own calming system to help the stress response stay proportionate. Not switched off. Just supported where it should be.

Chamomile Extract

A single chamomile flower with a yellow centre and white petals

Chamomile Extract

STRESS · RELAXATION SUPPORT

Supports relaxation and better sleep. Chamomile’s natural compounds support relaxation and normal digestive comfort.

GABA (Gamma-
Aminobutyric Acid)

GABA (Gamma-
Aminobutyric Acid)

STRESS · NERVOUS SYSTEM FUNCTION

Helps balance neurotransmitter activity during stressful situations by acting as the nervous system's natural 'off' switch. When the nervous system is stimulated, GABA is a naturally-occurring compound that helps support normal nervous system function and calm, balanced behavior.

L-Tryptophan

L-Tryptophan

STRESS · NERVOUS SYSTEM FUNCTION

Helps support healthy serotonin production for more balanced behavior. L-Tryptophan is the building block the body uses to support serotonin pathways – the long-term mood pathway. Consistent support means more balanced, settled behavior over time.

ACTIVE INGREDIENTS:

Relora®, Chamomile Extract, GABA (Gamma-Aminobutyric Acid), L-Tryptophan.

INACTIVE INGREDIENTS:

Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pollock Oil, Pork Spray Dried Liver, Rosemary Extract, Sunflower Lecithin, Tapioca Starch.

Relora® is used under license.

Not all supplements are created equal

390mg of actives
per 2 chews

A dense reddish-brown Wuffes chew standing beside a grey chew representing other calming supplements, separated by a thin white line

Others

Minimal actives.
More fillers.

How Wuffes Calming Chews compare with other calming supplements
	What the chew does	OTHERS
Yes	Promotes calm naturally, without the strong sedative effects	No
Yes	Melatonin-free	No
Yes	Powered by Relora® clinically validated to support normal cortisol response	No
Yes	Promotes long-term calm through healthy serotonin production	No

The vet advisory board that actually advises

Our vet partners don't just recommend our supplements. They know what you are really dealing with – the problems that don't go away and what good actually looks like. That knowledge shapes everything we make.

Dr. Tiffany Ruiz Da Silva, a Wuffes veterinary advisor, in a black vet jacket with a stethoscope, holding two Yorkshire terriers — Dr. Tiffany Ruiz Da SilvaVMD, cVMA | Canine Nutrition

Dr. Jennifer Repac, a Wuffes veterinary advisor, in a white lab coat with her arms folded — Dr. Jennifer RepacDVM, DACVSMR, CVA, CCRT, CVCH | Sports Medicine & Rehabilitation

The standards behind every supplement

Certified against the industry's gold standard

The NASC exists because pet supplements deserve the same rigour as the ones you'd take yourself.

We're proud to carry the NASC Quality Seal – awarded only to brands that pass a comprehensive independent audit and maintain ongoing compliance with rigorous quality standards.

It's the clearest signal a dog parent has that what's on the label is what's in the product. It can't be purchased. It has to be earned.

Every formula we make is held to the same three-part standard: The right ingredients, at the right concentrations, in the right blends.

Not because it's the easiest way to make a supplement. But because it's the right way to make one that works.

It's the difference between a product that looks good on a label and one that makes a real difference to your dog.

Every Wuffes formula is independently tested for quality, purity and potency once it leaves our facility.

It's an extra layer of accountability we built into our process – not because we're required to, but because if you're going to give something to your dog every day, it has to be exactly right.

Processing can degrade active ingredients, reducing their potency before the product even reaches your dog.

We test every formula post-manufacturing to verify that what we formulated is what survived. If the active ingredients didn't make it through intact, neither does the product.

Every ingredient in every Wuffes formula is there for a specific, documented reason. No wheat, corn, soy or potato. No unnecessary binders or fillers. No artificial colours or flavourings.

Where flavouring is needed, we use whole food flavours such as pork liver, not synthetic alternatives or derivatives.

Nothing enters the formula without justification. Nothing is there to bulk out the product or reduce cost.

A supplement your dog won't eat is no supplement at all – every dog parent knows that feeling.

The industry's answer to palatability (taste) testing is laboratory dogs. Kept in controlled environments, used specifically for this purpose. We don't think that's the right way to do it, and we never have.

So before any Wuffes formula goes to market, it's tested by real dogs, sourced from our own large community of dog parents. Simply put, if dogs don't like it, it doesn't make the cut.

Supplements take time to work. The active ingredients need time to build up, absorb, and begin working at a cellular level.

You make a commitment to your dog, so here's ours to you. 90 days to try it, stick with it and if you're not happy with the results – we'll make it right.

We're proud that less than 1% of our customers ever need to take us up on it.

Every Wuffes supplement is manufactured in certified facilities in the United States, held to some of the most rigorous production standards in the world.

FDA-registered, cGMP-compliant facilities where every stage of production, from raw material intake to finished product, is documented, audited, and held to a consistent standard.

*with globally sourced ingredients

A man in a brown hat sits on wooden porch steps feeding a chew to a curly-coated black dog, a jar of Wuffes chews in his other hand

What everyone else says

4.5

4.8

4.9

REAL DOGS. REAL REVIEWS.

From dog people, for dog people.

Not sure where to start? We can help.

Every dog is different. Tell us about yours and we’ll point you to the formula that fits. It takes less than a minute and saves you the guesswork. Plus you’ll get $5 off your first order.

Find my dog’s formula

FAQs

For all product FAQs please head to our FAQs page

Use your pet's weight to follow the recommended amount below:

0–35 lbs: 1 soft chew daily
36–65 lbs: 2 soft chews daily
66–100 lbs: 3 soft chews daily
101–120 lbs: 4 soft chews daily
Over 120 lbs: 5 soft chews daily

Our expertly formulated Calming Chews contain four clinically validated ingredients to support your pup's everyday stress and occasional anxiety – without the strong sedatives.

Here's how our calming chews can help:

Promotes relaxation, without sedation
Supports emotional balance and stress regulation
Helps promote calm behavior
Maintains normal cortisol levels
Supports healthy neurotransmitter activity (serotonin, GABA, dopamine)

Our chews are ideal for dogs who struggle with:

Occasional separation anxiety
Noise sensitivity (like fireworks or thunderstorms)
Travel or unfamiliar environments
General restlessness, pacing or hyper-alertness

Whether it's for a specific event or everyday stress, Calming Chews can help your dog stay cool, calm and confident.

Our Calming Chews are shelf stable and can be stored in your cupboard at room temperature for up to 3 months. If you intend to use the chews beyond 3 months, we recommend storing your chews in the fridge to preserve their freshness.

In order to look out for as many pups as possible, we formulated our chews with allergies in mind. If your pet is particularly sensitive, please note that Calming Chews includes Pork, Fish (wild Alaskan pollock oil) and Brewer's Yeast (gluten).

If your dog eats too many all at once, you can expect your dog to have minor issues such as gastrointestinal discomfort, including gas and bloating. These symptoms should subside in 2–3 days. If your dog has persistent vomiting and diarrhea, please consult your veterinarian. Your vet will make recommendations based on your pet's age, size and pre-existing conditions.

Our products are proudly made in the USA from globally sourced ingredients.

Every dog gets a little anxious now and then - but if your pup regularly seems unsettled, it could be a sign they need some extra support. Our Calming Chews are a gentle way to help ease those everyday stresses.

Here are some common signs your dog may benefit from Wuffes Calming Chews:

Pacing or struggling to relax
Whining, barking, or howling for no clear reason
Easily startled or always on alert
Shaking or trembling (not from cold)
Panting even when calm or cool
Hiding or trying to escape certain situations
Chewing, digging, or scratching when left alone
Changes in appetite - eating much more or much less
Repetitive behaviors like constant licking or tail chasing
Accidents indoors despite being house-trained

If you're noticing any of these, it might be time to talk with your vet about adding a calming supplement to your dog's routine. Many pet parents find that even small changes can make a big difference in their dog's comfort and behavior.

Our supplements are built to work together, so you can stack our everyday formulas alongside a balanced diet with no issue. If your dog is already taking another supplement or a prescription medication, talk to your vet before combining.

Active Ingredients per Chew (3g):

Relora® (Proprietary blend of Magnolia officinalis and Phellodendron amurense) – 75mg
Chamomile Extract – 50mg
GABA (Gamma-Aminobutyric Acid) – 35mg
L-Tryptophan – 35mg

Inactive Ingredients:

Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pork Spray Dried Liver, Rosemary Extract, Tapioca Starch, Pollock Oil, Sunflower Lecithin.

*Relora® is used under license.

Calming Chews

Ingredients

Results Timeline

Serving Guide

Ingredients

Results Timeline

Serving Guide

Ingredients

Results Timeline

Serving Guide

Ingredients

Results Timeline

Serving Guide

Ingredients

Results Timeline

Serving Guide

50% of Dogs Suffer From Fear and Anxiety in The US*

Benefits

1Promotes Relaxation

2Helps Support a Normal Stress Response

3Helps Regulate Their Cortisol Response

4Supports Balanced, Steady Behavior

More 5 star reviews than anyone else? That's us.

Results Timeline

WEEK 1LAY THE GROUNDWORK

WEEKS 2–3SOMETHING'S STARTING TO SHIFT

WEEKS 4–6YOU'LL SEE IT. THEY'LL FEEL IT.

WEEKS 6–8IN FULL FORCE

Start before the stress hits

How we raise the bar

Real dogs. Real results.

TRUSTED BY OVER 1.3 MILLION DOG PEOPLE. You're in good company.

The Wuffes Standard™

The right ingredients

The right concentrations

The right blends

What's inside?

Relora®

Chamomile Extract

GABA (Gamma-Aminobutyric Acid)

L-Tryptophan

See all ingredients

Not all supplements are created equal

The vet advisory board that actually advises

The standards behind every supplement

Certified against the industry's gold standard

NASC Certified

The Wuffes Standard™

Third Party Tested

Active Ingredient Verified

Ingredient Integrity Verified

Community Taste Tested

The 90-Day Promise

Made in USA*

What everyone else says

REAL DOGS. REAL REVIEWS.

Not sure where to start? We can help.

FAQs

How many should I give my pup?

How can it benefit my dog?

How should it be stored?

Does it contain any allergens?

What happens if my pup eats them all at once?

Where is it made?

How do I know if my pet needs a calming supplement?

Can it be used with other supplements or prescription medication?

What are the ingredients?

GABA (Gamma-
Aminobutyric Acid)