Name: Allergy & Itch Chews
Brand: Wuffes
SKU: IASC50
Availability: InStock

Made in the USA*
*from globally sourced ingredients
Scientifically Formulated
3rd Party Tested
The 90-Day Promise
No Artificial Colors
No Artificial Preservatives

9 out of 10 Dogs Are ‘Itchy Dogs’*

Seasonal allergies don't need covering up. Your dog needs real support. Our Allergy & Itch Chews are formulated to go after the cause – supporting the immune response, the histamine response and your dog’s skin barrier. The three things behind every itch, every flare-up, every scratchy season.

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A low-angle close-up of a tan short-coated dog's chest and front leg against a blue sky

*Source: Elanco Animal Health.

Benefits

For dogs whose immune system overreacts to the world around them – pollen, grass, dust – helping it respond calmly instead of sending everything into overdrive.

For dogs that scratch, lick and itch from the inside out – targeting the histamine pathway at the source, before the overreaction becomes a full reaction.

For dogs with red, irritated or sensitive skin – supporting the skin barrier so it stays comfortable and resilient through every season.

For dogs that struggle every season without fail – working with the body's natural defenses so results last beyond the serving.

Two border collies playing in a sunlit field of tall golden grass, one lying down and panting happily in the foreground.

More 5 star reviews than anyone else? That's us.

4.5

*Based on 5 star Trustpilot reviews among US dog supplement brands as of September 2026. Source: Trustpilot.

Results Timeline

Our supplements are built for the long game. The more consistent you are, the harder they work.

A Cavalier King Charles Spaniel takes a Wuffes Allergy & Itch Chew from its owner's hand in a sunlit hayfield, with the product jar visible in her other hand.

WEEK 1LAY THE GROUNDWORK

The Colostrum and Omega-3s for skin support and immune response support are starting to get absorbed. Things are in motion.

A Cavalier King Charles Spaniel stands on its hind legs, reaching up toward its owner's hand in a tall, golden hayfield.

WEEKS 2–3SOMETHING'S STARTING TO SHIFT

The Quercetin and Turkey Tail Mushroom in our chews are starting to properly support the immune response. Some dogs start showing early signs of skin comfort. You might even notice before they tell you.

Close-up of a Cavalier King Charles Spaniel's windblown face, ears lifted by the breeze, mouth open, standing in dry golden grass.

WEEKS 4–6YOU'LL SEE IT. THEY'LL FEEL IT.

Now, Vitamin E and Omega-3s are actively supporting normal skin barrier function through the season. Calmer skin and a balanced immune response are starting to take effect. This is where the benefits start to really show.

A Cavalier King Charles Spaniel lies in tall grass while its owner pets its back, holding a jar of Wuffes Allergy & Itch Chews.

WEEKS 6–8IN FULL FORCE

Their natural defenses are now working hand-in-hand with the supplement. Dogs that used to struggle through every season are holding their own. Keep going. This is what long-term balance feels like, and consistency is what maintains it.

Remember: Every dog is different. Size, age, where they're starting from – it all plays a part. Daily use is what makes the difference. These are supplements, not quick fixes.

Why we built it

Watching your dog scratch, lick and react season after season is exhausting. And heartbreaking. Most other supplements don’t look at the source. But, our Allergy & Itch Chews are formulated to go deeper – supporting the immune response, the histamine response and the skin barrier. The three things behind every itch, every flare-up, every scratchy season. Not another temporary fix. Finally, something built to last.

A golden retriever sniffs a Wuffes jar held out by a woman in a straw hat sitting on the grass

How we raise the bar

Triple-Action Support. One Daily Chew.

Colostrum and Turkey Tail Mushroom support normal immune function. Quercetin supports a normal histamine response. Omega-3 Algae Oil and Vitamin E provide antioxidant support and maintain the skin barrier.

Guaranteed 50% IgG Colostrum

Not all Colostrum is equal. IgG — the antibody that does the immune heavy lifting — has to be present at the right concentration to make a difference. Ours is standardized to 50% IgG. This means that every chew your dog eats contains the same concentration of the antibody that matters. We don't believe in diluting what works.

Not Your Average Omega-3.

Our Omega-3's come from Algae Oil — the original source fish get their Omega-3s from. More concentrated, more targeted for skin barrier support, and at 105mg per chew, we didn't compromise on the amount either.

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Real dogs. Real results.

The moment you notice your dog is back to themselves – we never get tired of hearing it.

Allergy & Itch Chews

Golden Retriever

I began giving her the allergy chew and the sneezing and scratching calmed better than Benadryl! I haven’t heard a sneezing fit since the first week and now the hot spots have finally been able to heal since she’s no long constantly scratching at them, it’s been a lifesaver for us.

Cailin G.

Allergy & Itch Chews

Shih Tzu

These chews are amazing for both dogs. I have noticed substantially less itchy and they seem more at peace without the constant scratching. I would strongly recommend!

Charles G.

A fawn mastiff-type dog lies on a patterned rug with a chewed plush toy between its paws

Allergy & Itch Chews

Cane Corso

Used this during the spring to boost my 13yo Cane Corso. Can definitely say that it helps during the peak pollen days. And yes, she stays on this daily during the peak

Tony M.

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The Wuffes Standard™

Scientific principles we obsess over, because every milligram matters.

The right ingredients

5 clinically studied actives, each with a specific job. Colostrum at 50% IgG for immune support, Algae Oil Omega-3s for the skin barrier, Quercetin for the histamine response, Turkey Tail Mushroom for immune balance, and Vitamin E for antioxidant support.
The right concentrations

It's not enough to have the right ingredients. They need to show up in the right amounts. Each 2-chew serving delivers 720mg of actives, clinically designed to have a real effect.
The right blends

Each ingredient targets a specific area, but they work together to achieve the same goal; better skin and immune health.
Colostrum (50% IgG) and Turkey Tail Mushroom support normal immune function. Quercetin supports a normal histamine response. And Omega-3 Algae Oil and Vitamin E help maintain the skin barrier and provide antioxidant support.

What's inside?

Clinically-tested ingredients picked for a purpose and crafted into a blend that makes use of every milligram.

Omega-3 Algae Oil

A clump of dark green dried algae, viewed from above

Omega-3 Algae Oil

ITCHING · OCCASIONAL ALLERGIES · SKIN SUPPORT

Helps support healthy skin with its rich omega-3 fatty acid content to maintain skin hydration and provide the nutritional support for a healthy inflammatory response.

Colostrum (50% IgG)

A thick smear of pale cream-coloured colostrum

Colostrum (50% IgG)

ITCHING · OCCASIONAL ALLERGIES · IMMUNE RESPONSE

Supports a healthy immune response through its rich concentration of compounds and proteins that strengthen the body's natural defenses.

Vitamin E

A round pile of pale sunflower seed kernels, viewed from above

Vitamin E

ITCHING · OCCASIONAL ALLERGIES · SKIN SUPPORT

Helps keep skin calm, clear and strong by protecting cells from oxidative stress caused by metabolic processes and environmental exposure.

PRODUCTSALLERGY & ITCH CHEWSMULTIVITAMIN CHEWS

Turkey Tail Mushroom

ITCHING · OCCASIONAL ALLERGIES · IMMUNE SUPPORT

Helps support a balanced immune system and a normal immune response by containing 20% Polysaccharides per mg. These are the active compounds that actually support immune and gut health.

Quercetin

A red onion sliced in half, showing its layered rings

Quercetin

ITCHING · OCCASIONAL ALLERGIES · HISTAMINE RESPONSE

Helps support a healthy histamine response by stabilizing the cells that release histamine.

ACTIVE INGREDIENTS:

Omega-3s (From Algae Oil), Colostrum (50% IgG), Vitamin E (d-alpha-tocopherol), Turkey Tail Mushroom, Quercetin Dihydrate.

INACTIVE INGREDIENTS:

Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pollock Oil, Pork Spray Dried Liver, Rosemary Extract, Sunflower Lecithin, Tapioca Starch.

Not all chews are created equal

720mg of actives
per 2 chews

A dense reddish-brown Wuffes chew standing beside a grey chew representing other allergy chews, separated by a thin white line

Others

Minimal actives.
More fillers.

How Wuffes Allergy & Itch Chews compare with other allergy chews
	What the chew does	OTHERS
Yes	Formulated with Omega-3s dogs can actually absorb	No
Yes	Colostrum standardized to 50% IgG in every batch	No
Yes	Triple action formula: immune response, histamine response & skin barrier support	No
Yes	Formulated with five clinically-tested active ingredients	No
Yes	Works with your dog's natural immune response for lasting results	No

The vet advisory board that actually advises

Our vet partners don't just recommend our supplements. They know what you are really dealing with – the problems that don't go away and what good actually looks like. That knowledge shapes everything we make.

Dr. Tiffany Ruiz Da Silva, a Wuffes veterinary advisor, in a black vet jacket with a stethoscope, holding two Yorkshire terriers — Dr. Tiffany Ruiz Da SilvaVMD, cVMA | Canine Nutrition

Dr. Jennifer Repac, a Wuffes veterinary advisor, in a white lab coat with her arms folded — Dr. Jennifer RepacDVM, DACVSMR, CVA, CCRT, CVCH | Sports Medicine & Rehabilitation

The standards behind every supplement

Certified against the industry's gold standard

The NASC exists because pet supplements deserve the same rigour as the ones you'd take yourself.

We're proud to carry the NASC Quality Seal – awarded only to brands that pass a comprehensive independent audit and maintain ongoing compliance with rigorous quality standards.

It's the clearest signal a dog parent has that what's on the label is what's in the product. It can't be purchased. It has to be earned.

Every formula we make is held to the same three-part standard: The right ingredients, at the right concentrations, in the right blends.

Not because it's the easiest way to make a supplement. But because it's the right way to make one that works.

It's the difference between a product that looks good on a label and one that makes a real difference to your dog.

Every Wuffes formula is independently tested for quality, purity and potency once it leaves our facility.

It's an extra layer of accountability we built into our process – not because we're required to, but because if you're going to give something to your dog every day, it has to be exactly right.

Processing can degrade active ingredients, reducing their potency before the product even reaches your dog.

We test every formula post-manufacturing to verify that what we formulated is what survived. If the active ingredients didn't make it through intact, neither does the product.

Every ingredient in every Wuffes formula is there for a specific, documented reason. No wheat, corn, soy or potato. No unnecessary binders or fillers. No artificial colours or flavourings.

Where flavouring is needed, we use whole food flavours such as pork liver, not synthetic alternatives or derivatives.

Nothing enters the formula without justification. Nothing is there to bulk out the product or reduce cost.

A supplement your dog won't eat is no supplement at all – every dog parent knows that feeling.

The industry's answer to palatability (taste) testing is laboratory dogs. Kept in controlled environments, used specifically for this purpose. We don't think that's the right way to do it, and we never have.

So before any Wuffes formula goes to market, it's tested by real dogs, sourced from our own large community of dog parents. Simply put, if dogs don't like it, it doesn't make the cut.

Supplements take time to work. The active ingredients need time to build up, absorb, and begin working at a cellular level.

You make a commitment to your dog, so here's ours to you. 90 days to try it, stick with it and if you're not happy with the results – we'll make it right.

We're proud that less than 1% of our customers ever need to take us up on it.

Every Wuffes supplement is manufactured in certified facilities in the United States, held to some of the most rigorous production standards in the world.

FDA-registered, cGMP-compliant facilities where every stage of production, from raw material intake to finished product, is documented, audited, and held to a consistent standard.

*with globally sourced ingredients

A man in a brown hat sits on wooden porch steps feeding a chew to a curly-coated black dog, a jar of Wuffes chews in his other hand

What everyone else says

4.5

4.8

4.9

REAL DOGS. REAL REVIEWS.

From dog people, for dog people.

Not sure where to start? We can help.

Every dog is different. Tell us about yours and we’ll point you to the formula that fits. It takes less than a minute and saves you the guesswork. Plus you’ll get $5 off your first order.

Find my dog’s formula

FAQs

For all product FAQs please head to our FAQs page

Use your pet's weight to follow the recommended amount below:

0–35 lbs: 1 soft chew daily
36–65 lbs: 2 soft chews daily
66–100 lbs: 3 soft chews daily
101–120 lbs: 4 soft chews daily
Over 120 lbs: 5 soft chews daily

Just like us, dogs can have allergic reactions to things like pollen, dust, mold, or certain foods. If your pup deals with constant scratching, watery eyes, or skin flare-ups, adding a gentle allergy supplement to their daily routine can make a big difference.

Here's how Wuffes Allergy & Itch Chews can help:

Supports a balanced immune response to reduce overreactions to common allergens
Helps maintain healthy skin and reduce itching, redness, and hot spots
Eases allergy-related discomfort by promoting a normal inflammatory response
Helps calm histamine reactions like sneezing, watery eyes, and irritation
Offers support for food sensitivities, including tummy trouble or chronic itching
Delivers powerful antioxidants to help protect your pup's skin and cells from stress
Can be used proactively during allergy seasons to reduce the intensity of flare-ups

Our allergy chews are shelf stable and can be stored in your cupboard at room temperature for up to 3 months. If you intend to use the chews beyond 3 months, we recommend storing your chews in the fridge to preserve their freshness.

In order to look out for as many pups as possible, we formulated our chews with allergies in mind. If your pet is particularly sensitive, please note that Allergy & Itch Chews includes Pork, Fish (wild alaskan pollock oil) and Brewer's Yeast (gluten).

Wuffes Allergy & Itch Chew is formulated with safe, well-tolerated ingredients. However, exceeding the recommended amount may cause mild digestive upset. Always follow the feeding guide and consult your vet before exceeding the recommendation. If your pet accidentally ingests more than the recommended amount, monitor for symptoms and consult your veterinarian if concerns arise.

Our products are proudly made in the USA from globally sourced ingredients.

Here's how Wuffes Allergy & Itch Chews can help:

Supports a balanced immune response to reduce overreactions to common allergens
Helps maintain healthy skin and reduce itching, redness, and hot spots
Eases allergy-related discomfort by promoting a normal inflammatory response
Helps calm histamine reactions like sneezing, watery eyes, and irritation
Offers support for food sensitivities, including tummy trouble or chronic itching
Delivers powerful antioxidants to help protect your pup's skin and cells from stress
Can be used proactively during allergy seasons to reduce the intensity of flare-ups

Whether your dog deals with occasional seasonal flare-ups or more regular sensitivities, this chew is designed to help them feel more comfortable - and more like themselves again.

Our supplements are built to work together, so you can stack our everyday formulas alongside a balanced diet with no issue. If your dog is already taking another supplement or a prescription medication, or if your dog is on immunosuppressive therapy or has complex medical conditions, consult your veterinarian before use.

Active Ingredients per chew (3g)

Omega 3s (from Algae Oil) – 105 mg
Colostrum (50% IgG) – 100 mg
Vitamin E (d-alpha-tocopherol) – 80 mg
Turkey Tail Mushroom (20% Polysaccharides) – 50 mg
Quercetin Dihydrate – 25 mg

Inactive Ingredients

Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Rosemary Extract, Spray Dried Pork Liver, Sunflower Lecithin, Tapioca Starch, Wild Alaskan Pollock Oil

(Note: An account will only be available if you've completed your purchase as a "subscription." One-time orders will not create an account.)

You can click on the user icon at the top right of the page, next to the shopping cart, or use the "Manage my subscription" option in our Help Center. Enter the email associated with your Wuffes purchase and a one-time login code will be sent to you — check your spam folder if it does not arrive.

We're proud to say that every Wuffes product is made right here in the USA—crafted with care and held to the highest quality standards. We use a mix of domestically and globally sourced ingredients, carefully selected for their safety, effectiveness, and benefits for your pup's health.

From production to packaging, we're committed to delivering trustworthy supplements that you (and your dog) can feel good about.

We know your furry friend can't wait to receive their Wuffes, and with all that tail-waggling, all they mean is "Is it here yet?!". Don't worry, we won't keep you waiting! All orders placed before noon are shipped on the same day, while all other orders will ship within 1 business day.

e.g. If your order is placed on a Friday at 9:00 am, your order will be shipped the same day. If your order is placed on a Friday at 2:00 pm, your order will be shipped until the next Monday.

Where Does Wuffes Ship From?

Wuffes orders ship from the USA. We fulfill orders from three warehouses located in Tracy, CA, Addison, IL, and Atlanta, GA.

More zoomies on the way?

We totally get wanting the best for your mama-to-be! Since our supplements haven't been tested on pregnant or nursing dogs, we recommend checking with your vet first to make sure it's the safest choice for her and her pups.

My dog ate the whole tub—what now?

Don't panic—we know pups can be sneaky snackers! If your dog polished off an entire tub of our Advanced Hip & Joint Support (as long as it's made for their weight), they should be just fine. You might notice some mild symptoms like vomiting, diarrhea, or an upset tummy.

If they got into more than one tub, a tub for a different weight or symptoms last longer than 24 hours, it's best to check in with your vet just to be safe. And of course, we're here if you need us!

In the case of our 23-in-1 Multivitamin, certain vitamins (such as Vitamin D3) can cause toxicity in large doses. If you think they've eaten too much, it's always best to be safe and speak to your vet.

Allergy & Itch Chews

Ingredients

Results Timeline

Serving Guide

Ingredients

Results Timeline

Serving Guide

Ingredients

Results Timeline

Serving Guide

Ingredients

Results Timeline

Serving Guide

Ingredients

Results Timeline

Serving Guide

9 out of 10 Dogs Are ‘Itchy Dogs’*

Benefits

1Supports a Balanced Immune Response

2Promotes a Normal Histamine Response

3Promotes Healthy Skin

4Built for the Long Term

More 5 star reviews than anyone else? That's us.

Results Timeline

WEEK 1LAY THE GROUNDWORK

WEEKS 2–3SOMETHING'S STARTING TO SHIFT

WEEKS 4–6YOU'LL SEE IT. THEY'LL FEEL IT.

WEEKS 6–8IN FULL FORCE

Why we built it

How we raise the bar

Real dogs. Real results.

The Wuffes Standard™

The right ingredients

The right concentrations

The right blends

What's inside?

Omega-3 Algae Oil

Colostrum (50% IgG)

Vitamin E

Turkey Tail Mushroom

Quercetin

See all ingredients

Not all chews are created equal

The vet advisory board that actually advises

The standards behind every supplement

Certified against the industry's gold standard

NASC Certified

The Wuffes Standard™

Third Party Tested

Active Ingredient Verified

Ingredient Integrity Verified

Community Taste Tested

The 90-Day Promise

Made in USA*

What everyone else says

REAL DOGS. REAL REVIEWS.

Not sure where to start? We can help.

FAQs

How many should I give my pup?

How can it benefit my dog?

How should it be stored?

Does it contain any allergens?

What happens if my pet eats them all at once?

Where is it made?

How do I know if my pet needs an allergy supplement?

Can it be used with other supplements or prescription medication?

What are the ingredients?

Where can I find my account?

Where are your products made?

How long do orders take to ship?

Where are your products shipped from?

Can I give Wuffes supplements to a pregnant dog?

Can my pet overdose?