Kick pesky occasional allergies and itching to the curb, with a blend of clinically tested, skin-soothing ingredients, designed to regulate – not suppress – their natural immune response. Relief you can feel. Comfort they deserve.
Provides long-term support
Regulates immune response
Soothes irritated skin

Now NASC-Certified: Quality You Can Trust
-
Safety you can trust
The NASC Seal guarantees that our supplements meet strict safety standards
-
Independently audited
Our manufacturing is third-party audited for full transparency
-
Clear labeling
Our product labels meet the NASC’s strict guidelines.
-
High quality standards
We ensure purity and consistency in every [tub/bottle]
-
Committed to transparency
From ingredients to packaging, we provide full transparency
-
Backed by experts
Our products meet top industry standards, with vet input.

As Seen In
Our scientifically-proven ingredients have been scrutinized in thousands of studies, and are meticulously selected for their combined effect to enhance joint health & mobility.
Glucosamine
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
Featured In:
The Research
The Research
The Research
The Research
- Effects of Chondroitin Supplementation on OA (page 284-288)
- GLU/CHO Method of Action
- GLU/CHO Improves OA
The Research
The Research
- Fish Oil Supplementation Reduces Inflammatory Markers in Dogs with OA
- Omega 3 Supplementation Improves Mobility in Dogs with OA
- Omega 3 Supplementation Improves Clinical Signs of OA in Dogs
The Research
The Research
The Research
- UC-II Combo Supplement
- UC-II Mechanism of Action
- UC-II Anti-Inflammatory Effects
- UC-II Pain Reduction
- UC-II Immune Suppression
- UC-II vs. Pharma
- UC-II Review
The Research
The Research
- Importance of Zinc in Canine Health
- Zinc Supplementation Supports Positive Canine Behaviour
- Zinc Supports Skin Health
- Huskies and Malamutes Prone to Zinc Deficiency
The Research
The Research
- Efficacy of Vitamin D Supplementation in Dogs
- Role of Vitamin D in Canine Health
- Impact of Vitamin D in Canine Diseases
The Research
The Research
- Taurine Supplementation Supports Treatment of Heart Disease
- Dietary Taurine and Heart Disease
- Dilated Cardiomyopathy and Taurine Deficiency
- DCM and Golden Retrievers
The Research
The Research
The Research
The Research
The Research
The Research
The Research
The Research
The Research
The Research
- Role of Magnesium in Canine Health
- Effects of Magnesium Deficiency
- Supplementation of Magnesium Reduces Stress in Dogs
The Research
The Research
The Research
The Research
The Research
- Fish Oil Supplementation Reduces Inflammatory Markers in Dogs with OA
- Omega 3 Supplementation Improves Mobility in Dogs with OA
- Omega 3 Supplementation Improves Clinical Signs of OA in Dogs
Our Veterinary Advisory Board
Our esteemed Veterinary Advisory Board consists of renowned professionals with years of experience in animal health. From board-certified orthopedic surgeons to veterinary nutritionists and rehabilitation specialists, each member brings a wealth of knowledge and insight to our team.
Subscription Benefits
-
Save up to 26% + 5 Free Gifts
-
Unlock exclusive savings and bonus gifts worth $199.
-
Hassle-Free Deliveries
-
You set the schedule - monthly, bimonthly, or whatever works best for your pup.
-
Flexible Management
-
Pause, skip, or update anytime. You're in charge.
-
90-Day Money-Back Guarantee
-
Try it risk-free. No results? Get a full refund.

FAQs
For all product FAQs please head to our FAQs page
Where can I find my account?
(Note: An account will only be available if you've completed your purchase as a "subscription." One-time orders will not create an account.)
1. You can click on the user icon on the top right of the page - right next to the shopping cart.


Alternatively, you can also access through the "Manage my subscription" option available in our "Help Center".

3. Enter the email associated with your Wuffes purchase , and a 1 time login code will be sent to your email address. Please make sure to check on your Spam folder!



4. Enter the code, and you are all set!

💡 Troubles signing in? We highly recommend clearing the cookies & cache on your web browser, as well as your browsing history, restart your web browser and try to log in one more time!
💡 Not receiving the verification code? Do not worry! The verification code may sometimes be detected as "spam" by your email's filtering system, so please make sure to check your spam folder!
Where are your products made?
We’re proud to say that every Wuffes product is made right here in the USA—crafted with care and held to the highest quality standards. We use a mix of domestically and globally sourced ingredients, carefully selected for their safety, effectiveness, and benefits for your pup’s health.
From production to packaging, we’re committed to delivering trustworthy supplements that you (and your dog) can feel good about.
How long do orders take to ship?
We know your furry friend can't wait to receive their Wuffes, and with all that tail-waggling, all they mean is "Is it here yet?!". Don't worry, we won’t keep you waiting! All orders placed before noon are shipped on the same day, while all other orders will ship within 1 business day.
| Time your order is placed | Shipping time |
| Before 12:00 pm (midday) | Shipped the same day |
| After 12:00 pm (midday) | Shipped within 1 business day (Monday–Friday, except Holidays) |
e.g. If your order is placed on a Friday at 9:00 am, your order will be shipped the same day. If your order is placed on a Friday at 2:00 pm, your order will be shipped until the next Monday.
Where are your products shipped from?
Where do Wuffes orders come from?
All of our products are proudly made in the USA and shipped straight from our warehouse in Denver, Colorado—packed with care and ready to head your way!
Can I give Wuffes supplements to a pregnant dog?
More zoomies on the way?
We totally get wanting the best for your mama-to-be! Since our supplements haven’t been tested on pregnant or nursing dogs, we recommend checking with your vet first to make sure it’s the safest choice for her and her pups.
Can my pet overdose?
My dog ate the whole tub—what now?
Don’t panic—we know pups can be sneaky snackers! If your dog polished off an entire tub of our Advanced Hip & Joint Support (as long as it's made for their weight), they should be just fine. You might notice some mild symptoms like vomiting, diarrhea, or an upset tummy.
If they got into more than one tub, a tub for a different weight or symptoms last longer than 24 hours, it’s best to check in with your vet just to be safe. And of course, we’re here if you need us!
In the case of our 23-in-1 Multivitamin, certain vitamins (such as Vitamin D3) can cause toxicity in large doses. If you think they’ve eaten too much, it’s always best to be safe and speak to your vet.
Do pets need joint supplements?
Great question! Just like humans, dogs’ joints go through wear and tear—especially as they age, stay active, or belong to larger breeds prone to joint issues. Joint supplements help support mobility, reduce stiffness, and cushion their joints so they can stay active, playful, and pain-free.
Even younger pups can benefit! Starting early can help maintain healthy joints down the line.
How do I know if my pet needs a joint supplement?
With 1 in 5 dogs developing joint issues in their lifetime (reference), it’s very important for pet parents to look out for and recognise signs of joint discomfort. Some signs to look out for include:
- Limping
- Difficulty stand up and/or lying down
- Shaking legs
- Uneven weight bearing and/or favoring one side
These are also very common signs of other issues. If your pet exhibits one or more of these, please consult your veterinarian.
Can it be used with other supplements or prescription medication?
Absolutely! Our joint chews are designed to play nice with other supplements and medications—as long as you’re following the recommended serving guidelines.
If your pup is on a prescription or has a medical condition, a quick check-in with your vet is always a good idea.




















































