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Over 750,000 Dogs Helped
The Simple Solution to Relieve Stress & Separation Anxiety
You don’t have to choose between a stressed dog and a "zombie" dog.
Is your dog struggling with a world that's too loud and too fast?
To us, it’s just a doorbell, a car ride, or a thunderstorm. To your dog, it’s a sensory overload that triggers a "fight or flight" response.
Almost 50% of dogs show significant signs of fear or anxiety*, often resulting in:
Barking or Whining
Pacing or Restlessness
Destructive Behaviour
Hiding or Attempting to Escape
Ears Pinned Back or Tail Tucked
Trembling or Shaking
*Source: Texas A&M College of Veterinary Medicine.
RESTORE THEIR PEACE TODAY
A Vet-Approved Daily Chew Designed To Restore Their Peace & Calm
Wuffes Calming chews are formulated with four clinically tested ingredients – designed to help dogs manage everyday stress without sedation.
Clinically Tested Ingredients
Formulated with a full clinical dose of Relora® and three other research-backed ingredients.
Promotes Calm Behavior
Helps your dog stay relaxed during the day without "zombie-like" tiredness found in sedative products.
Supports Emotional Balance
Helps to regulate serotonin and dopamine, keeping your dog's mood stable and predictable.
Maintains Normal Cortisol Levels
Specifically targets the "stress hormone" at its source to prevent the physical and mental toll of chronic hyper-vigilance.
Helps Dogs in Stressful Events
Provides the support needed to navigate fireworks, vet visits, and separation anxiety with much less distress.
Loved by Picky Eaters
A delicious, daily soft chew that even fussy dogs eat like a treat – making it stress free for both of you.
This synergistic blend helps regulate cortisol and calm neurotransmitters like serotonin, GABA, and dopamine to support emotional stability and relaxation.
RESTORE THEIR PEACE TODAY
Recommended by veterinarians, trusted by pet parents
Dr. Meghan Barrett
DVM, cVMA, CCRT, CVFT, FFCP, CCVN
Dr. Tiffany Ruiz-Da Silva
VMD, cVMA
Smudge
Wuffes Calming Chew Superfan
Charlie
Wuffes Calming Chew Superfan
Based on verified customer reviews on
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With Fast-Acting Relora®
A powerful, natural blend of Magnolia and Phellodendron bark extracts.
It helps manage everyday stress by gently regulating cortisol – the body’s main stress hormone - and supporting calming brain chemicals like GABA and serotonin.
Results in as little as 2-4 weeks!
If you’re not happy after 3 motnhs of consistent use, we’ll refund you.
Promotes Calm Behaviour
Supports with Separation Anxiety
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90-Day Money-Back Guarantee
You’ve Probably Tried These Solutions... But They Don’t Work
The "Placebo" Chews
The "Sedatives"
Behavioral Training
Punishment or Crating
Training Collars
How Does It Work?
Wuffes Calming Chews are formulated with four clinically researched and effective ingredients.
A patented ingredient that is clinically proven to help manage stress by supporting the normal cortisol response – without sedation.
Promotes a calm, yet alert state – perfect for training anxious dogs
The ‘feel-good’ chemical that helps regulate mood and behavior. The more serotonin, the better your pup’s mood.
A known-and-loved extract that promotes relaxation, helps with sleep and maintains natural balance of serotonin and GABA.
Based on large breed formula for dogs over 65 lbs.
Third-Party Tested
GMO, Hormone & Antibiotic Free
Manufactured in USA
Made in a GMP Facility
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In a Sea of Competition, Why Trust Wuffes?
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COST PER CHEW
CLINICALLY STUDIED AMOUNT
ACTIVES PROVEN TO CALM
NASC APPROVED
TOTAL ACTIVE INGREDIENTS PER SERVING
MONEY-BACK GUARANTEE
VETERINARIAN APPROVED
Uses the clinically studied dose of Relora® – the perfect amount to benefit dogs
✅
Our four hero ingredients are scientifically proven to create a calming effect
330 mg
With the highest quality, globally-sourced ingredients
90-Day Money-Back Guarantee
Our esteemed Veterinary Advisory Board approve every single formulation
EVERYONE ELSE
❌
Most use ingredients that aren't clinically proven at their clinically studied dose
❌
Other brands use some credible ingredients, but they also use around 80% of filler ingredients that can be inflammatory
Very few brands pass the rigorous NASC standards.
Around 150–250 mg
Lots of brands make their products in China with little to no quality control.
Other brands offer a 30-Day Money-Back Guarantee, but our testing reveals that they haven't ever processed a refund.
No dedicated Veterinary Advisory Board
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Now NASC-Certified: Quality You Can Trust
Wuffes is now proud to to be accredited by the NASC, an industry mark of trust and transparency. Our certification means that every product you give to your dog meets the highest standards of safety and quality. Learn more about what this seal means for you and your pet's health.
Safety You Can Trust
The NASC Seal guarantees that our supplements meet strict safety standards
Independently Audited
Our manufacturing is third-party audited for full transparency
Clear Labelling
Our product labels meet the NASC’s strict guidelines
High Quality Standards
We ensure purity and consistency in every tub
Committed to Transparency
From ingredients to packaging, we provide full transparency
Backed by Experts
Our products meet top industry standards, with vet input
Our standards go beyond industry expectations
Your dog's health is too important for shortcuts. That's why every batch of our chews are made with the highest quality controls in place.
GMO, Homone & Antibiotic-Free
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FIGHT HIP & JOINT PAIN – RESTORE MOBILITY & COMFORT!
#1 Highest Reviewed Hip & Joint Supplement for Dogs*
OUR BIGGEST DISCOUNT
Excellent 4.8 | 3.2k Reviews
STOP STRESS & ANXIETY - RESTORE PEACE & CALM!
Excellent 4.8 | 3.2k Reviews
Dog Size:
0-35 lbs
35-65 lbs
65-100 lbs
100-120 lbs
Over 120 lbs
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Pause or cancel anytime
One-time purchase
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We recommend at least 3 months of consistent use to see results*
- KCKasey C.Verified ReviewerReviewingCalming ChewsI recommend this productPet Age 7-9 years oldPet Size 60-80lbsRated 5 out of 5 starsYesterdayAbsolute win with all 5 of my dogs!
I was pleasantly surprised by these calming chews. All five of my dogs enjoyed the taste, which is a huge win on its own since they can be picky. While the chews didn’t completely eliminate their anxiety, they absolutely took the edge off and helped them relax during stressful situations. I noticed they were calmer, more settled, and able to recover more quickly without being drowsy or “out of it.” These chews feel like a gentle, natural support rather than a sedative, which is exactly what I was hoping for. After trying them, we added them to our subscription, and I’ll definitely keep these on hand for times when my dogs need a little extra help staying calm! I definitely recommend them! More effective than other calming chews that I have purchased in the past!
- SDSahar D.ReviewingCalming ChewsI recommend this productRated 5 out of 5 stars4 days agoEasy to Add to Routine
This supplement fits right into our dog’s daily schedule. No issues so far and he takes it without hesitation.
- DCDavid C.ReviewingCalming ChewsI recommend this productRated 5 out of 5 stars6 days ago10 yo pitty
It seems to be helping her at lot !
- KSKathy S.ReviewingCalming ChewsI recommend this productRated 5 out of 5 stars1 week agoLily can relax again
After 3 weeks of taking Wuffes, she’s chillin’ like she used to all day long! We’re so grateful!
- KVKristin V. V.ReviewingCalming ChewsI recommend this productRated 5 out of 5 stars1 week agoMy girls love them!
My dogs have been taking these supplements for quite a while and they seem to be doing great! Thank you all!!👍😍
Frequently Asked Questions
How many chews should I give my dog?
Use your pet’s weight to follow the recommended amount below.
How can it benefit my dog?
Our expertly formulated chews contain four clinically proven ingredients to help your pup feel more relaxed and balanced – without the strong sedatives. Whether it’s thunder, travel, new environments, new people or spending time alone, it’s about time they felt less nervous, stressed and out of it. Benefits include:
Easing signs of anxiety and nervousness
Supporting calmer behavior in stressful situations, like car rides or visits to the vet.
Helps regulate the stress hormone, cortisol
Promotes a healthy, more stable stress response
Supports mood balancing brain chemicals
Boosts natural calming neurotransmitters, including serotonin and GABA
Promotes emotional stability without sedation
Keep your dog relaxed, but still alert, playful and full of personality
Our chews are ideal for dogs who struggle with:
Separation anxiety
Noise sensitivity (including fireworks or thunderstorms)
Travel or unfamiliar environments
General restlessness, pacing, or hyperalertness
How should the chews be stored?
Our Calming Chews for dogs are shelf stable unopened for 2 years. You can store them in your cupboard at room temperature for up to 3 months. If you intend to use the chews after 3 months, we recommend storing your chews in the fridge to preserve their freshness.
Do the chews contain any allergens?
In order to look out for as many pups as possible, we formulated our chews with allergies in mind. If you or your pet is particularly sensitive, please note that Calming Chews contain Pork Liver, Fish (Wild Alaskan Pollock Oil) and Brewer’s Yeast (gluten).
Can my dog overdose on these chews?
Our chews are formulated with safe, well tolerated ingredients. However, exceeding the recommended dose may cause mild digestive upset. Always follow the directions for use and consult your vet before starting any new supplement. If your pet accidentally consumes more than the recommended dose, monitor for symptoms and consult your veterinarian if concerns arise.
What happens if my dog eats these chews all at once?
If your dog eats too many all at once, you can expect your dog to have minor issues, such as gastrointestinal discomfort – like gas and bloating. These symptoms should subside in 2-3 days. If your dog has persistent vomiting and diarrhea, please consult your veterinarian. Your vet will make recommendations based on your pet’s age, size and pre-existing conditions.
Where are these chews made?
Our chews are proudly made in the USA from globally sourced ingredients.
How do I know if my dog needs a calming supplement?
Every dog gets a little anxious now and then, but if your pup regularly seems unsettled, it could be a sign they need some extra support. Our Calming Chews are a gentle way to help ease those everyday stresses. Here are some common signs your dog may benefit from our chews:
Pacing or struggling to relax
Whining, barking, or howling for no clear reason
Easily startled or always on alert
Shaking or trembling (not from cold)
Panting even when calm or cool
Hiding or trying to escape certain situations
Chewing, digging, or scratching when left alone
Changes in appetite – eating much more or much less
Repetitive behaviors like constant licking or tail chasing
Accidents indoors despite being housetrained
If you’re noticing any of these, it might be time to talk with your vet about adding a calming supplement to your dog’s routine. Many dog parents find that even small changes can make a big difference in their dog’s comfort and behavior.
Can these chews be used with other supplements or prescription medication?
Yes. These chews can generally be used alongside other supplements or medications. However, we recommend consulting your veterinarian if your dog has pre-existing conditions or is taking prescription drugs before starting any new supplement.
How old does my dog have to be to eat these chews?
These chews are suitable for pets over 6 months of age.
My dog has a health condition, are these chews suitable for them?
Our chews are formulated with gentle, well tolerated ingredients and are typically safe for dogs with common health conditions. Still, we recommend checking with your veterinarian before use, particularly if your dog has a chronic illness or is on medication.
Are these chews safe for cats?
These chews are specifically formulated for dogs and have not been tested for safety or efficacy in cats.
Cats have different metabolic and neurological responses to supplements, particularly to ingredients like L-Theanine, Chamomile, and Relora®. We do not recommend giving this product to cats unless specifically directed and approved by a veterinarian.
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© 2025 Statements on wuffes.com have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.
*With globally sourced ingredients**Results may vary