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Over 750,000 Dogs Helped

The Simple Solution to Relieve Stress & Separation Anxiety

You don’t have to choose between a stressed dog and a "zombie" dog.

RESTORE THEIR PEACE TODAY

Is your dog struggling with a world that's too loud and too fast?

To us, it’s just a doorbell, a car ride, or a thunderstorm. To your dog, it’s a sensory overload that triggers a "fight or flight" response.

Almost 50% of dogs show significant signs of fear or anxiety*, often resulting in:

Barking or Whining

Lip Licking or Tail Chasing

Pacing or Restlessness

Destructive Behaviour

Frequent Peeing Indoors

Hiding or Attempting to Escape

Ears Pinned Back or Tail Tucked

Trembling or Shaking

*Source: Texas A&M College of Veterinary Medicine.

RESTORE THEIR PEACE TODAY

A Scientifically-Formulated Daily Chew Designed To Restore Their Peace & Calm

Wuffes Calming chews are formulated with four clinically tested ingredients – designed to help dogs manage everyday stress without sedation.

Clinically Tested Ingredients
Formulated with a full clinical dose of Relora® and three other research-backed ingredients.

Promotes Calm Behavior 

Helps your dog stay relaxed during the day without "zombie-like" tiredness found in sedative products.

Supports Emotional Balance
Helps to regulate serotonin and dopamine, keeping your dog's mood stable and predictable.

Maintains Normal Cortisol Levels
Specifically targets the "stress hormone" at its source to prevent the physical and mental toll of chronic hyper-vigilance.

Helps Dogs in Stressful Events 

Provides the support needed to navigate fireworks, vet visits, and separation anxiety with much less distress.

Loved by Picky Eaters

A delicious, daily soft chew that even fussy dogs eat like a treat – making it stress free for both of you.

This synergistic blend helps regulate cortisol and calm neurotransmitters like serotonin, GABA, and dopamine to support emotional stability and relaxation.

RESTORE THEIR PEACE TODAY

Trusted by professionals, and by pet parents

Dr. Meghan Barrett

DVM, cVMA, CCRT, CVFT, FFCP, CCVN

Dr. Tiffany Ruiz-Da Silva

VMD, cVMA

Smudge

Wuffes Calming Chew Superfan

Charlie

Wuffes Calming Chew Superfan

Based on verified customer reviews on

Slide 1 of 3

TRY CALM NOW

With Fast-Acting Relora®

A powerful, natural blend of Magnolia and Phellodendron bark extracts.
It helps manage everyday stress by gently regulating cortisol – the body’s main stress hormone - and supporting calming brain chemicals like GABA and serotonin.

Results in as little as 2-4 weeks!

If you’re not happy after 3 months of consistent use, we’ll refund you.

Promotes Calm Behaviour

Supports Emotional Balance
Maintains Normal Cortisol Levels
Helps in Stressful Events

Supports with Separation Anxiety

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90-Day Money-Back Guarantee

You’ve Probably Tried These Solutions... But They Don’t Work

The "Placebo" Chews

The "Sedatives"

Behavioral Training

Punishment or Crating

Extra Walks

Training Collars

How Does It Work?

Wuffes Calming Chews are formulated with four clinically researched and effective ingredients.

Relora®

A patented ingredient that is clinically proven to help manage stress by supporting the normal cortisol response – without sedation.

GABA

Promotes a calm, yet alert state – perfect for training anxious dogs

L-Tryptophan

The ‘feel-good’ chemical that helps regulate mood and behavior. The more serotonin, the better your pup’s mood.

Chamomile

A known-and-loved extract that promotes relaxation, helps with sleep and maintains natural balance of serotonin and GABA.

Based on large breed formula for dogs over 65 lbs.

Third-Party Tested

GMO, Hormone & Antibiotic Free

Circular badge with stars and stripes, 'Made in USA' text.

Manufactured in USA

Circle with 'GMP' and a crown above the letters.

Made in a GMP Facility

TRY CALM NOW -->

In a Sea of Competition, Why Trust Wuffes?

TRY NOW AND GET 40% OFF

COST PER CHEW

CLINICALLY STUDIED AMOUNT

ACTIVES PROVEN TO CALM

NASC APPROVED

TOTAL ACTIVE INGREDIENTS PER SERVING

MADE IN USA

MONEY-BACK GUARANTEE

VET APPROVED

$0.41
🧪

Uses the clinically studied dose of Relora® – the perfect amount to benefit dogs

Our four hero ingredients are scientifically proven to create a calming effect

💪🏻

330 mg

With the highest quality, globally-sourced ingredients

90-Day Money-Back Guarantee

Our products are trusted by veterinary professionals.

EVERYONE ELSE

$0.44 – $1+

Most use ingredients that aren't clinically proven at their clinically studied dose

Other brands use some credible ingredients, but they also use around 80% of filler ingredients that can be inflammatory

🤷🏼

Very few brands pass the rigorous NASC standards.

👎

Around 150–250 mg

💩

Lots of brands make their products in China with little to no quality control.

🤷🏼

Other brands offer a 30-Day Money-Back Guarantee, but our testing reveals that they haven't ever processed a refund.

No dedicated Veterinary Advisory Board

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Now NASC-Certified: Quality You Can Trust

Wuffes is now proud to to be accredited by the NASC, an industry mark of trust and transparency. Our certification means that every product you give to your dog meets the highest standards of safety and quality. Learn more about what this seal means for you and your pet's health.


Safety You Can Trust

The NASC Seal guarantees that our supplements meet strict safety standards

Independently Audited

Our manufacturing is third-party audited for full transparency

Clear Labelling

Our product labels meet the NASC’s strict guidelines

High Quality Standards

We ensure purity and consistency in every tub

Committed to Transparency

From ingredients to packaging, we provide full transparency

Backed by Experts

Our products meet top industry standards. 

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Our standards go beyond industry expectations

Your dog's health is too important for shortcuts. That's why every batch of our chews are made with the highest quality controls in place.

With Globally Sourced Ingredients
Batch Tested
No Artificial Colors or Flavors

GMO, Homone & Antibiotic-Free

GMP/SQF Certified
In Line With FDA CVM Guidelines

TRY CHEWS WITH 40% OFF

STOP STRESS & ANXIETY - RESTORE PEACE & CALM!

TrustScore 4.7 | 4,000+ Reviews

Our expertly formulated Calming Chews contain four clinically proven ingredients to support your pup’s everyday stress and occasional anxiety – without the strong sedatives.

1. Select Your Dog’s Weight:

2. Choose Your Plan:

In stock, ready to ship

Reviews Summary
Customers say these calming chews help their dogs feel more relaxed and less anxious. Many report noticeable improvements in their pets' reactions to loud noises, storms, and stressful situations like grooming or car rides. Dogs appear calmer during bedtime routines and show reduced barking at everyday disturbances. Pet owners appreciate that the chews provide gentle relaxation without making dogs drowsy or sedated. Most dogs enjoy the taste and take them willingly. Several customers mention seeing gradual improvements over 2-3 weeks of consistent use. While some owners with dogs having severe anxiety note limited effectiveness, the majority find these chews helpful for managing their pets' stress levels naturally.
Customers Talked About
4.7
Rated 4.7 out of 5 stars
Based on 57 reviews
91%would recommend these products
Great tasteRated 4.7 on a scale of 1 to 5
Slide 1 selected
57 reviews
  • JF
    Jeanette F.
    Verified Buyer
    Reviewing
    Calming Chews
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    Great stuff

    It’s a great product and my dogs love it

    The only problem is that I have one jar that is so tight nobody can open

    Great tasteRated 5.0 on a scale of 1 to 5
  • AR
    Allison R.
    Verified Buyer
    Reviewing
    Calming Chews
    I recommend this product
    Pet Age 13 or older
    Pet Size Under 20lbs
    Rated 5 out of 5 stars
    1 month ago
    Calmer senior dog

    Our senior dog (almost 17 yrs old) was experiencing constant shaking legs. After about two months on the Calming Chews, she barely shakes anymore. She also doesn't get upset about thunder and fireworks anymore.

    Great tasteRated 5.0 on a scale of 1 to 5
  • MK
    Maci K.
    Verified Buyer
    Reviewing
    Calming Chews
    I recommend this product
    Pet Age 10-12 years old
    Pet Size 20-40lbs
    Rated 5 out of 5 stars
    2 months ago
    More Comfortable Every Day

    My dog just seems happier moving around. It's not one big change—it's lots of little improvements that add up.

    Great tasteRated 5.0 on a scale of 1 to 5
  • BL
    Bobbi L. P.
    Verified Buyer
    Reviewing
    Calming Chews
    I recommend this product
    Pet Age 10-12 years old
    Pet Size 40-60lbs
    Rated 5 out of 5 stars
    2 months ago
    Excellent Product

    My dog has responded great to this product.

    I will continue to use these chews as long as possible.

    Great tasteRated 5.0 on a scale of 1 to 5
  • ST
    Susan T.
    Verified Buyer
    Reviewing
    Calming Chews
    I recommend this product
    Pet Age 1-3 years old
    Pet Size 20-40lbs
    Rated 5 out of 5 stars
    2 months ago
    Wonderful product

    Wonderful products

    Great tasteRated 5.0 on a scale of 1 to 5

Frequently Asked Questions

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© 2025 Statements on wuffes.com have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

*With globally sourced ingredients**Results may vary