Allergy & Itch Chews
180g / 6.35oz / 60 chews
Helps inflammatory response
Eases itching
Supports immune reaction
Order within
Order
Today
Ships
Today
Arrives
4 days from now

Dr. Meghan Barrett
DVM, cVMA, CCRT, CVFT, FFCP, CCVN

Dr. Tiffany Ruiz-Da Silva
VMD, cVMA

Jessie
Allergy & Itch Chews Superfan

Benny
Allergy & Itch Chews Superfan

Poppy
Allergy & Itch Chews Superfan
What plenty of pup owners dismiss as quirks, is often your dog responding to frustrating allergies.
Whether it’s a change in season or your pup is genetically bred to have an allergy, they can feel like they come out of nowhere, with no real solution.
Spot the Signs of Allergies:

Itching and scratching

Paw licking and chewing

Rubbing
Redness and skin irritation

Hot spots

Allergy related discomfort

Sneezing, water eyes, general irritation
Tummy trouble
*Source: PR News Wire
Relief They Can Feel, Comfort They Deserve
If your dog shows any of these signs, pesky allergies might be the cause. Targeted support is their best bet at feeling loads better.
When to Use
For seasonal allergies take 1-2 months before for maximum effectiveness.
Directions for Use
0-35 lbs
1 Soft Chew daily
36-65 lbs
2 Soft Chews daily
66-100 lbs
3 Soft Chews Daily
101-120 lbs
4 Soft Chews Daily
Over 121 lbs
5 Soft Chews Daily
We recommend giving supplements as part of their normal routine
Build Your Defense
Defending against seasonally heightened allergies and itches is a long game. Consistent, everyday use helps maintain balanced immune function and ongoing skin comfort all year long.
Built for proactive immune support – not quick fixes
Helps maintain the normal histamine response
Promotes calm, comfortable skin
Sensitive pups won't experience any side-effects with our hypoallergenic formula
Why Wuffes?
EVERYONE ELSE
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COST PER CHEW |
$0.54 |
$0.54 – $1+ |
CLINICALLY TESTED INGREDIENTS |
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❌ |
SUPPORTS NORMAL ALLERGY RESPONSE |
✅ |
❌ |
COLOSTRUM (IGG) QUALITY |
✅ |
👎 |
NON-DROWSY |
✅ |
🤷🏼 |
HYPOALLERGENIC |
✅ |
❌ |
NASC APPROVED |
✅ |
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MONEY-BACK GUARANTEE |
✅ |
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MADE IN USA |
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The ingredients in our Allergy & Itch have been scrutinized in thousands of studies, and are meticulously selected for their combined effect to reduce stress and promote calm.
Colostrum - with 50% lgG
Featured In:
Featured In:
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The Research
- Supports mucosal immune function in dogs, including increased secretory IgA levels, helping maintain gut and skin barrier integrity (Satyaraj et al., 2013).
- Helps maintain balanced immune signaling, including support of normal IgE activity, contributing to healthy immune responses to environmental exposures (Satyaraj et al., 2013).
- Demonstrates support for healthy immune markers and normal vaccine response in canine studies, reflecting broad immunological support (Satyaraj et al., 2013).
- Supports intestinal barrier integrity and healthy immune tolerance mechanisms, key components of balanced immune function (Playford et al., 2000).
ACTIVE INGREDIENTS PER CHEW, (3g)
- Omega 3s (from Algae Oil) – 105 mg
- Colostrum (50% IgG) – 100 mg
- Vitamin E (d-alpha-tocopherol) – 80 mg
- Turkey Tail Mushroom (20% Polysaccharides) – 50 mg
- Quercetin Dihydrate – 25 mg
INACTIVE INGREDIENTS
- Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pollock Oil, Pork Spray Dried Liver, Rosemary Extract, Sunflower Lecithin, Tapioca Starch.
The Research
- Supports healthy mast cell function and helps maintain normal histamine and leukotriene release as part of balanced immune responses (Morikawa et al., 2003).
- Helps support healthy cytokine signaling, including IL-4, IL-6, and TNF-α pathways, contributing to balanced Th1/Th2 immune activity (Mlcek et al., 2016).
- Supports intestinal barrier integrity and healthy gut function, important for maintaining appropriate immune responses to dietary and environmental exposures (Mlcek et al., 2016).
- Provides plant-derived support for long-term immune balance as part of a daily wellness approach (Mlcek et al., 2016).
ACTIVE INGREDIENTS PER CHEW, (3g)
- Omega 3s (from Algae Oil) – 105 mg
- Colostrum (50% IgG) – 100 mg
- Vitamin E (d-alpha-tocopherol) – 80 mg
- Turkey Tail Mushroom (20% Polysaccharides) – 50 mg
- Quercetin Dihydrate – 25 mg
INACTIVE INGREDIENTS
- Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pollock Oil, Pork Spray Dried Liver, Rosemary Extract, Sunflower Lecithin, Tapioca Starch.
The Research
- Supports healthy cytokine balance, including TNF-α, IL-6, and IL-10 pathways, contributing to normal immune signaling in dogs (Benson et al., 2019).
- Helps maintain healthy T-cell and natural killer (NK) cell activity as part of balanced immune function (Benson et al., 2019).
- Supports a healthy gut microbiome environment, reinforcing the gut–skin connection and overall immune resilience (Benson et al., 2019).
- Provides beta-glucans and polysaccharides (PSK and PSP) that support long-term immune balance and healthy inflammatory responses (Camilleri et al., 2024).
ACTIVE INGREDIENTS PER CHEW, (3g)
- Omega 3s (from Algae Oil) – 105 mg
- Colostrum (50% IgG) – 100 mg
- Vitamin E (d-alpha-tocopherol) – 80 mg
- Turkey Tail Mushroom (20% Polysaccharides) – 50 mg
- Quercetin Dihydrate – 25 mg
INACTIVE INGREDIENTS
- Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pollock Oil, Pork Spray Dried Liver, Rosemary Extract, Sunflower Lecithin, Tapioca Starch.
The Research
- A study supporting the bioavailability of algae-derived Omega 3s EPA/DHA in dogs (Dahms et al., 2019)
- Algae oil provides essential fatty acids for a healthy coat and supports antioxidant pathways in dogs (Zhang et al., 2025)
- Omega 3 fatty acids support long-term skin barrier health in dogs (Kareem at al., 2025)
- A review of the the beneficial effects of Omega 3 supplementation for skin health in dogs (Kaur et al., 2024
ACTIVE INGREDIENTS PER CHEW, (3g)
- Omega 3s (from Algae Oil) – 105 mg
- Colostrum (50% IgG) – 100 mg
- Vitamin E (d-alpha-tocopherol) – 80 mg
- Turkey Tail Mushroom (20% Polysaccharides) – 50 mg
- Quercetin Dihydrate – 25 mg
INACTIVE INGREDIENTS
- Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pollock Oil, Pork Spray Dried Liver, Rosemary Extract, Sunflower Lecithin, Tapioca Starch.
The Research
- Supports healthy skin condition and overall dermal integrity in dogs (Plevnik Kapun et al., 2014).
- Helps maintain antioxidant enzyme activity (SOD and GPX), supporting protection against oxidative stress in skin tissue (Plevnik Kapun et al., 2014).
- Contributes to balanced oxidative status, supporting normal inflammatory pathways and skin health (Plevnik Kapun et al., 2014).
- Provides antioxidant support that helps maintain healthy skin structure as part of a comprehensive immune-support routine (Plevnik Kapun et al., 2014).
ACTIVE INGREDIENTS PER CHEW, (3g)
- Omega 3s (from Algae Oil) – 105 mg
- Colostrum (50% IgG) – 100 mg
- Vitamin E (d-alpha-tocopherol) – 80 mg
- Turkey Tail Mushroom (20% Polysaccharides) – 50 mg
- Quercetin Dihydrate – 25 mg
INACTIVE INGREDIENTS
- Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pollock Oil, Pork Spray Dried Liver, Rosemary Extract, Sunflower Lecithin, Tapioca Starch.
Proudly NASC-Certified
Tested for quality
All supplements are rigorously tested and audited
Trusted ingredients
Only high-quality, traceable ingredients
Manufactured safely
We follow Good Manufacturing Practices for consistency.
Trust in every tub
The NASC Seal guarantees uncompromised quality
Clear and transparent
Our labels give you full transparency about ingredients.
Scientifically formulated
Developed with veterinary professionals to ensure top quality

These reviews are for informational purposes only. The information is not a substitute for expert veterinary care. Reviews are written by actual customers and represent their own observations. These observations are not guaranteed, are not medically substantiated, and may not be typical for other pets. When necessary, reviews will be replied to privately.
FAQS
For all product FAQs please head to our FAQs page
How many should I give my pup?
Use your pet’s weight to follow the recommended amount below:
Weight Category | Directions for Use |
0-35lbs | 1 soft chew daily |
36-65lbs | 2 soft chews daily |
66-100lbs | 3 soft chews daily |
101-120lbs | 4 soft chews daily |
120+lbs | 5 soft chews daily |
How can it benefit my dog?
Just like us, dogs can have allergic reactions to things like pollen, dust, mold, or certain foods. If your pup deals with constant scratching, watery eyes, or skin flare-ups, adding a gentle allergy supplement to their daily routine can make a big difference.
Here’s how Wuffes Allergy & Itch Chews can help:
- Supports a balanced immune response to reduce overreactions to common allergens
- Helps maintain healthy skin and reduce itching, redness, and hot spots
- Eases allergy-related discomfort by promoting a normal inflammatory response
- Helps calm histamine reactions like sneezing, watery eyes, and irritation
- Offers support for food sensitivities, including tummy trouble or chronic itching
- Delivers powerful antioxidants to help protect your pup’s skin and cells from stress
- Can be used proactively during allergy seasons to reduce the intensity of flare-ups
How should it be stored?
Our allergy chews are shelf stable and can be stored in your cupboard at room temperature for up to 3 months. If you intend to use the chews beyond 3 months, we recommend storing your chews in the fridge to preserve their freshness.
Does it contain any allergens?
In order to look out for as many pups as possible, we formulated our chews with allergies in mind. If your pet is particularly sensitive, please note that Allergy & Itch Chews includes Pork, Fish (wild alaskan pollock oil) and Brewer’s Yeast (gluten).
Can my pet overdose?
Wuffes Allergy & Itch Chew is formulated with safe, well-tolerated ingredients. However, exceeding the recommended dose may cause mild digestive upset. Always follow the feeding guide and consult your vet before giving additional doses. If your pet accidentally consumes more than the recommended dose, monitor for symptoms and consult your veterinarian if concerns arise.
Where is it made?
Our products are proudly made in the USA from globally sourced ingredients.
How do I know if my pet needs an allergy supplement?
Just like us, dogs can have allergic reactions to things like pollen, dust, mold, or certain foods. If your pup deals with constant scratching, watery eyes, or skin flare-ups, adding a gentle allergy supplement to their daily routine can make a big difference.
Here’s how Wuffes Allergy & Itch Chews can help:
- Supports a balanced immune response to reduce overreactions to common allergens
- Helps maintain healthy skin and reduce itching, redness, and hot spots
- Eases allergy-related discomfort by promoting a normal inflammatory response
- Helps calm histamine reactions like sneezing, watery eyes, and irritation
- Offers support for food sensitivities, including tummy trouble or chronic itching
- Delivers powerful antioxidants to help protect your pup’s skin and cells from stress
- Can be used proactively during allergy seasons to reduce the intensity of flare-ups
Whether your dog deals with occasional seasonal flare-ups or more regular sensitivities, this chew is designed to help them feel more comfortable - and more like themselves again.
Can it be used with other supplements or prescription medication?
Yes, this formula can typically be used alongside other supplements and medications. However, if your dog is on immunosuppressive therapy or has complex medical conditions, consult your veterinarian before use.
Is it safe for cats?
Wuffes Advanced Allergy & Itch Chew is specifically formulated for dogs and has not been tested for safety or efficacy in cats. Because cats have different metabolic and neurological responses to supplements, we do not recommend giving this product to cats unless directed by a veterinarian.
What are the ingredients?
Active Ingredients per chew (3g)
Omega 3s (from Algae Oil) – 105 mg
Colostrum (50% IgG) – 100 mg
Vitamin E (d-alpha-tocopherol) – 80 mg
Turkey Tail Mushroom (20% Polysaccharides) – 50 mg
Quercetin Dihydrate – 25 mg
Inactive Ingredients
Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Rosemary Extract, Spray Dried Pork Liver, Sunflower Lecithin, Tapioca Starch, Wild Alaskan Pollock Oil
Where can I find my account?
(Note: An account will only be available if you've completed your purchase as a "subscription." One-time orders will not create an account.)
1. You can click on the user icon on the top right of the page - right next to the shopping cart.


Alternatively, you can also access through the "Manage my subscription" option available in our "Help Center".

3. Enter the email associated with your Wuffes purchase , and a 1 time login code will be sent to your email address. Please make sure to check on your Spam folder!



4. Enter the code, and you are all set!

💡 Troubles signing in? We highly recommend clearing the cookies & cache on your web browser, as well as your browsing history, restart your web browser and try to log in one more time!
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Where are your products made?
We’re proud to say that every Wuffes product is made right here in the USA—crafted with care and held to the highest quality standards. We use a mix of domestically and globally sourced ingredients, carefully selected for their safety, effectiveness, and benefits for your pup’s health.
From production to packaging, we’re committed to delivering trustworthy supplements that you (and your dog) can feel good about.
How long do orders take to ship?
We know your furry friend can't wait to receive their Wuffes, and with all that tail-waggling, all they mean is "Is it here yet?!". Don't worry, we won’t keep you waiting! All orders placed before noon are shipped on the same day, while all other orders will ship within 1 business day.
| Time your order is placed | Shipping time |
| Before 12:00 pm (midday) | Shipped the same day |
| After 12:00 pm (midday) | Shipped within 1 business day (Monday–Friday, except Holidays) |
e.g. If your order is placed on a Friday at 9:00 am, your order will be shipped the same day. If your order is placed on a Friday at 2:00 pm, your order will be shipped until the next Monday.
Where are your products shipped from?
Where Does Wuffes Ship From?
Wuffes orders ship from the USA. We fulfill orders from three warehouses located in Tracy, CA, Addison, IL, and Atlanta, GA.
Can I give Wuffes supplements to a pregnant dog?
More zoomies on the way?
We totally get wanting the best for your mama-to-be! Since our supplements haven’t been tested on pregnant or nursing dogs, we recommend checking with your vet first to make sure it’s the safest choice for her and her pups.
Can my pet overdose?
My dog ate the whole tub—what now?
Don’t panic—we know pups can be sneaky snackers! If your dog polished off an entire tub of our Advanced Hip & Joint Support (as long as it's made for their weight), they should be just fine. You might notice some mild symptoms like vomiting, diarrhea, or an upset tummy.
If they got into more than one tub, a tub for a different weight or symptoms last longer than 24 hours, it’s best to check in with your vet just to be safe. And of course, we’re here if you need us!
In the case of our 23-in-1 Multivitamin, certain vitamins (such as Vitamin D3) can cause toxicity in large doses. If you think they’ve eaten too much, it’s always best to be safe and speak to your vet.
Do pets need joint supplements?
Great question! Just like humans, dogs’ joints go through wear and tear—especially as they age, stay active, or belong to larger breeds prone to joint issues. Joint supplements help support mobility, reduce stiffness, and cushion their joints so they can stay active, playful, and pain-free.
Even younger pups can benefit! Starting early can help maintain healthy joints down the line.
How do I know if my pet needs a joint supplement?
With 1 in 5 dogs developing joint issues in their lifetime (reference), it’s very important for pet parents to look out for and recognise signs of joint discomfort. Some signs to look out for include:
- Limping
- Difficulty stand up and/or lying down
- Shaking legs
- Uneven weight bearing and/or favoring one side
These are also very common signs of other issues. If your pet exhibits one or more of these, please consult your veterinarian.
Can it be used with other supplements or prescription medication?
Absolutely! Our joint chews are designed to play nice with other supplements and medications—as long as you’re following the recommended serving guidelines.
If your pup is on a prescription or has a medical condition, a quick check-in with your vet is always a good idea.
We’re so sure you’ll love our products, we offer a 90-day money back guarantee on all our edible supplements.






