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Over 750,000 Dogs Helped

The Simple Solution to Relieve Stress & Separation Anxiety

You don’t have to choose between a stressed dog and a "zombie" dog.

RESTORE THEIR PEACE TODAY

Is your dog struggling with a world that's too loud and too fast?

To us, it’s just a doorbell, a car ride, or a thunderstorm. To your dog, it’s a sensory overload that triggers a "fight or flight" response.

Almost 50% of dogs show significant signs of fear or anxiety*, often resulting in:

Barking or Whining

Lip Licking or Tail Chasing

Pacing or Restlessness

Destructive Behaviour

Frequent Peeing Indoors

Hiding or Attempting to Escape

Ears Pinned Back or Tail Tucked

Trembling or Shaking

*Source: Texas A&M College of Veterinary Medicine.

RESTORE THEIR PEACE TODAY

A Scientifically-Formulated Daily Chew Designed To Restore Their Peace & Calm

Wuffes Calming chews are formulated with four clinically tested ingredients – designed to help dogs manage everyday stress without sedation.

Clinically Tested Ingredients
Formulated with a full clinical dose of Relora® and three other research-backed ingredients.

Promotes Calm Behavior 

Helps your dog stay relaxed during the day without "zombie-like" tiredness found in sedative products.

Supports Emotional Balance
Helps to regulate serotonin and dopamine, keeping your dog's mood stable and predictable.

Maintains Normal Cortisol Levels
Specifically targets the "stress hormone" at its source to prevent the physical and mental toll of chronic hyper-vigilance.

Helps Dogs in Stressful Events 

Provides the support needed to navigate fireworks, vet visits, and separation anxiety with much less distress.

Loved by Picky Eaters

A delicious, daily soft chew that even fussy dogs eat like a treat – making it stress free for both of you.

This synergistic blend helps regulate cortisol and calm neurotransmitters like serotonin, GABA, and dopamine to support emotional stability and relaxation.

RESTORE THEIR PEACE TODAY

Trusted by professionals, and by pet parents

Dr. Meghan Barrett

DVM, cVMA, CCRT, CVFT, FFCP, CCVN

Dr. Tiffany Ruiz-Da Silva

VMD, cVMA

Smudge

Wuffes Calming Chew Superfan

Charlie

Wuffes Calming Chew Superfan

Based on verified customer reviews on

Slide 1 of 3

TRY CALM NOW

With Fast-Acting Relora®

A powerful, natural blend of Magnolia and Phellodendron bark extracts.
It helps manage everyday stress by gently regulating cortisol – the body’s main stress hormone - and supporting calming brain chemicals like GABA and serotonin.

Results in as little as 2-4 weeks!

If you’re not happy after 3 months of consistent use, we’ll refund you.

Promotes Calm Behaviour

Supports Emotional Balance
Maintains Normal Cortisol Levels
Helps in Stressful Events

Supports with Separation Anxiety

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90-Day Money-Back Guarantee

You’ve Probably Tried These Solutions... But They Don’t Work

The "Placebo" Chews

The "Sedatives"

Behavioral Training

Punishment or Crating

Extra Walks

Training Collars

How Does It Work?

Wuffes Calming Chews are formulated with four clinically researched and effective ingredients.

Relora®

A patented ingredient that is clinically proven to help manage stress by supporting the normal cortisol response – without sedation.

L-Theanine

Promotes a calm, yet alert state – perfect for training anxious dogs

L-Tryptophan

The ‘feel-good’ chemical that helps regulate mood and behavior. The more serotonin, the better your pup’s mood.

Chamomile

A known-and-loved extract that promotes relaxation, helps with sleep and maintains natural balance of serotonin and GABA.

Based on large breed formula for dogs over 65 lbs.

Third-Party Tested

GMO, Hormone & Antibiotic Free

Circular badge with stars and stripes, 'Made in USA' text.

Manufactured in USA

Circle with 'GMP' and a crown above the letters.

Made in a GMP Facility

TRY CALM NOW -->

In a Sea of Competition, Why Trust Wuffes?

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COST PER CHEW

CLINICALLY STUDIED AMOUNT

ACTIVES PROVEN TO CALM

NASC APPROVED

TOTAL ACTIVE INGREDIENTS PER SERVING

MADE IN USA

MONEY-BACK GUARANTEE

VET APPROVED

$0.41
🧪

Uses the clinically studied dose of Relora® – the perfect amount to benefit dogs

Our four hero ingredients are scientifically proven to create a calming effect

💪🏻

330 mg

With the highest quality, globally-sourced ingredients

90-Day Money-Back Guarantee

Our products are trusted by veterinary professionals.

EVERYONE ELSE

$0.44 – $1+

Most use ingredients that aren't clinically proven at their clinically studied dose

Other brands use some credible ingredients, but they also use around 80% of filler ingredients that can be inflammatory

🤷🏼

Very few brands pass the rigorous NASC standards.

👎

Around 150–250 mg

💩

Lots of brands make their products in China with little to no quality control.

🤷🏼

Other brands offer a 30-Day Money-Back Guarantee, but our testing reveals that they haven't ever processed a refund.

No dedicated Veterinary Advisory Board

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Now NASC-Certified: Quality You Can Trust

Wuffes is now proud to to be accredited by the NASC, an industry mark of trust and transparency. Our certification means that every product you give to your dog meets the highest standards of safety and quality. Learn more about what this seal means for you and your pet's health.


Safety You Can Trust

The NASC Seal guarantees that our supplements meet strict safety standards

Independently Audited

Our manufacturing is third-party audited for full transparency

Clear Labelling

Our product labels meet the NASC’s strict guidelines

High Quality Standards

We ensure purity and consistency in every tub

Committed to Transparency

From ingredients to packaging, we provide full transparency

Backed by Experts

Our products meet top industry standards. 

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Our standards go beyond industry expectations

Your dog's health is too important for shortcuts. That's why every batch of our chews are made with the highest quality controls in place.

With Globally Sourced Ingredients
Batch Tested
No Artificial Colors or Flavors

GMO, Homone & Antibiotic-Free

GMP/SQF Certified
In Line With FDA CVM Guidelines

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STOP STRESS & ANXIETY - RESTORE PEACE & CALM!

OUR BIGGEST DISCOUNT

TrustScore 4.8 | 3,500+ Reviews

STOP STRESS & ANXIETY - RESTORE PEACE & CALM!

OUR BIGGEST DISCOUNT

TrustScore 4.8 | 3,500+ Reviews

Dog Size:

In stock, ready to ship

We recommend at least 3 months of consistent use to see results*

4.7
Rated 4.7 out of 5 stars
Based on 48 reviews
Total 5 star reviews: 37 Total 4 star reviews: 6 Total 3 star reviews: 5 Total 2 star reviews: 0 Total 1 star reviews: 0
90%would recommend these products
Great tasteRated 4.6 on a scale of 1 to 5
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48 reviews
  • NP
    Norma P.
    Verified Reviewer
    Reviewing
    Calming Chews
    I recommend this product
    Pet Age 7-9 years old
    Pet Size 20-40lbs
    Rated 5 out of 5 stars
    1 month ago
    Pups approve!

    My picky pups enjoy these chews and do not turn their nose up at them! We take them at bedtime and it helps us have a calm sleep routine. Would recommend!

    Great tasteRated 5.0 on a scale of 1 to 5
  • NP Profile picture for Nancy P.facebook logo
    Nancy P.
    Verified Reviewer
    Reviewing
    Calming Chews
    I recommend this product
    Pet Age 1-3 years old
    Pet Size 40-60lbs
    Rated 5 out of 5 stars
    1 month ago
    These chews are effective and apparently taste good too!

    We were sent a container of these chews for a dog that we sadly lost unexpectedly to cancer and bloat. She was a dreamboat and we adored her. We accepted the chews because we have 10 dogs and knew they would be useful...they were!

    We got 2 young German Shepherd/Husky mix fosters, Momma and Son, and they needed grooming badly. I gave them chews based on their weight before their grooming appointment and the groomer said they were the "best Husky mixes she's ever had!" I took that as a sign that the chews did their job! Both of them gobbled the chews up, so the taste must be pretty yummy.

    We have been using Wuffes products for years and I stand by their effectiveness and quality.

    Great tasteRated 5.0 on a scale of 1 to 5
  • MS Profile picture for Marc S.google logo
    Marc S.
    Verified Reviewer
    Reviewing
    Calming Chews
    I recommend this product
    Pet Age 10-12 years old
    Pet Size Over 100lbs
    Rated 5 out of 5 stars
    1 month ago
    Large Senior Dog

    My 150 LB dog, Camo is not very active in his later stage, but at times he would tend to seem a bit anxious about seeing being alone when I would leave for work. The effects from the calming chews seem to take the edge off and put him in a more relaxed content mood. I think that I additionally see him being a little happier. I do not give him the chews daily, only occasionally. He had never been a dog that gets wound up with noses or lots of activity outside, so I cannot attest to having a sedative effect to address a hyper sensitive temperament. It's reassuring to be able to give a product with natural ingredients, as opposed to prescribed medication. Camo has been on Wuffes joint supplement for years and I truly believe that they have provided relief and added longevity to his big boned, sore joint life. I certainly recommend this product!

    Great tasteRated 5.0 on a scale of 1 to 5
  • KL
    Kim L.
    Verified Reviewer
    Reviewing
    Calming Chews
    I recommend this product
    Pet Age 4-6 years old
    Pet Size 60-80lbs
    Rated 5 out of 5 stars
    1 month ago
    Amazing!!

    Our beautiful girl was previously abused. She was so skittish over the smallest noises. We have been giving them periodically to her. She's more relaxed. Thank you so much for the opportunity to try these.

    Great tasteRated 5.0 on a scale of 1 to 5
  • KK Profile picture for Kasey K.
    Kasey K.
    Verified Buyer
    Reviewing
    Calming Chews
    I recommend this product
    Pet Age 7-9 years old
    Pet Size 60-80lbs
    Rated 5 out of 5 stars
    1 month ago
    10 Paws Up!!!

    While two of my dogs experience anxiety, all five of my dogs liked the taste and thought that they were treats! They were easy to break apart of needed for smaller dogsFor my anxious dogs, it is a gentle, non-sedating calming support that definitely took the edge off. I noticed a difference in their behavior about two weeks into a daily dosage routine. Wuffes Calming Chews were much more effective other brands that I have tried in the past. I would definitely recommend them and continue my subscription!

    Great tasteRated 5.0 on a scale of 1 to 5

Frequently Asked Questions

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© 2025 Statements on wuffes.com have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

*With globally sourced ingredients**Results may vary