The ingredients in our Allergy & Itch have been scrutinized in thousands of studies, and are meticulously selected for their combined effect to reduce stress and promote calm.
Colostrum - with 50% lgG
Featured In:
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The Research
- Supports mucosal immune function in dogs, including increased secretory IgA levels, helping maintain gut and skin barrier integrity (Satyaraj et al., 2013).
- Helps maintain balanced immune signaling, including support of normal IgE activity, contributing to healthy immune responses to environmental exposures (Satyaraj et al., 2013).
- Demonstrates support for healthy immune markers and normal vaccine response in canine studies, reflecting broad immunological support (Satyaraj et al., 2013).
- Supports intestinal barrier integrity and healthy immune tolerance mechanisms, key components of balanced immune function (Playford et al., 2000).
ACTIVE INGREDIENTS PER CHEW, (3g)
- Omega 3s (from Algae Oil) – 105 mg
- Colostrum (50% IgG) – 100 mg
- Vitamin E (d-alpha-tocopherol) – 80 mg
- Turkey Tail Mushroom (20% Polysaccharides) – 50 mg
- Quercetin Dihydrate – 25 mg
INACTIVE INGREDIENTS
- Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pollock Oil, Pork Spray Dried Liver, Rosemary Extract, Sunflower Lecithin, Tapioca Starch.
The Research
- Supports healthy mast cell function and helps maintain normal histamine and leukotriene release as part of balanced immune responses (Morikawa et al., 2003).
- Helps support healthy cytokine signaling, including IL-4, IL-6, and TNF-α pathways, contributing to balanced Th1/Th2 immune activity (Mlcek et al., 2016).
- Supports intestinal barrier integrity and healthy gut function, important for maintaining appropriate immune responses to dietary and environmental exposures (Mlcek et al., 2016).
- Provides plant-derived support for long-term immune balance as part of a daily wellness approach (Mlcek et al., 2016).
ACTIVE INGREDIENTS PER CHEW, (3g)
- Omega 3s (from Algae Oil) – 105 mg
- Colostrum (50% IgG) – 100 mg
- Vitamin E (d-alpha-tocopherol) – 80 mg
- Turkey Tail Mushroom (20% Polysaccharides) – 50 mg
- Quercetin Dihydrate – 25 mg
INACTIVE INGREDIENTS
- Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pollock Oil, Pork Spray Dried Liver, Rosemary Extract, Sunflower Lecithin, Tapioca Starch.
The Research
- Supports healthy cytokine balance, including TNF-α, IL-6, and IL-10 pathways, contributing to normal immune signaling in dogs (Benson et al., 2019).
- Helps maintain healthy T-cell and natural killer (NK) cell activity as part of balanced immune function (Benson et al., 2019).
- Supports a healthy gut microbiome environment, reinforcing the gut–skin connection and overall immune resilience (Benson et al., 2019).
- Provides beta-glucans and polysaccharides (PSK and PSP) that support long-term immune balance and healthy inflammatory responses (Camilleri et al., 2024).
ACTIVE INGREDIENTS PER CHEW, (3g)
- Omega 3s (from Algae Oil) – 105 mg
- Colostrum (50% IgG) – 100 mg
- Vitamin E (d-alpha-tocopherol) – 80 mg
- Turkey Tail Mushroom (20% Polysaccharides) – 50 mg
- Quercetin Dihydrate – 25 mg
INACTIVE INGREDIENTS
- Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pollock Oil, Pork Spray Dried Liver, Rosemary Extract, Sunflower Lecithin, Tapioca Starch.
The Research
- A study supporting the bioavailability of algae-derived Omega 3s EPA/DHA in dogs (Dahms et al., 2019)
- Algae oil provides essential fatty acids for a healthy coat and supports antioxidant pathways in dogs (Zhang et al., 2025)
- Omega 3 fatty acids support long-term skin barrier health in dogs (Kareem at al., 2025)
- A review of the the beneficial effects of Omega 3 supplementation for skin health in dogs (Kaur et al., 2024
ACTIVE INGREDIENTS PER CHEW, (3g)
- Omega 3s (from Algae Oil) – 105 mg
- Colostrum (50% IgG) – 100 mg
- Vitamin E (d-alpha-tocopherol) – 80 mg
- Turkey Tail Mushroom (20% Polysaccharides) – 50 mg
- Quercetin Dihydrate – 25 mg
INACTIVE INGREDIENTS
- Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pollock Oil, Pork Spray Dried Liver, Rosemary Extract, Sunflower Lecithin, Tapioca Starch.
The Research
- Supports healthy skin condition and overall dermal integrity in dogs (Plevnik Kapun et al., 2014).
- Helps maintain antioxidant enzyme activity (SOD and GPX), supporting protection against oxidative stress in skin tissue (Plevnik Kapun et al., 2014).
- Contributes to balanced oxidative status, supporting normal inflammatory pathways and skin health (Plevnik Kapun et al., 2014).
- Provides antioxidant support that helps maintain healthy skin structure as part of a comprehensive immune-support routine (Plevnik Kapun et al., 2014).
ACTIVE INGREDIENTS PER CHEW, (3g)
- Omega 3s (from Algae Oil) – 105 mg
- Colostrum (50% IgG) – 100 mg
- Vitamin E (d-alpha-tocopherol) – 80 mg
- Turkey Tail Mushroom (20% Polysaccharides) – 50 mg
- Quercetin Dihydrate – 25 mg
INACTIVE INGREDIENTS
- Apple Cider Vinegar, Brewers Dried Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pollock Oil, Pork Spray Dried Liver, Rosemary Extract, Sunflower Lecithin, Tapioca Starch.
Relief They Can Feel, Comfort They Deserve
If your dog shows any of these signs, pesky allergies might be the cause. Targeted support is their best bet at feeling loads better.
When to Use
For seasonal allergies take 1-2 months before for maximum effectiveness.
Directions for Use
0-35 lbs
1 Soft Chew daily
36-65 lbs
2 Soft Chews daily
66-100 lbs
3 Soft Chews Daily
101-120 lbs
4 Soft Chews Daily
Over 121 lbs
5 Soft Chews Daily
We recommend giving supplements as part of their normal routine
Build Your Defense
Defending against seasonally heightened allergies and itches is a long game. Consistent, everyday use helps maintain balanced immune function and ongoing skin comfort all year long.
Built for proactive immune support – not quick fixes
Helps maintain the normal histamine response
Promotes calm, comfortable skin
Sensitive pups won't experience any side-effects with our hypoallergenic formula
Proudly NASC-Certified
Tested for quality
All supplements are rigorously tested and audited
Trusted ingredients
Only high-quality, traceable ingredients
Manufactured safely
We follow Good Manufacturing Practices for consistency.
Trust in every tub
The NASC Seal guarantees uncompromised quality
Clear and transparent
Our labels give you full transparency about ingredients.
Scientifically formulated
Developed with veterinary professionals to ensure top quality
What plenty of pup owners dismiss as quirks, is often your dog responding to frustrating allergies.
Whether it’s a change in season or your pup is genetically bred to have an allergy, they can feel like they come out of nowhere, with no real solution.
Spot the Signs of Allergies:
Itching and scratching
Paw licking and chewing
Rubbing
Redness and skin irritation
Hot spots
Allergy related discomfort
Sneezing, water eyes, general irritation
Tummy trouble
*Source: PR News Wire
Quality You Don’t Have to Question
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With Globally Sourced Ingredients
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Batch Tested
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No Artificial Colors or Flavors
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GMO, Hormone & Antibiotic free
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GMP/SQF Certified
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In line with FDA CVM Guidelines
How many chews should I give my dog?
Use your pet’s weight to follow the directions for use below.
How can I benefit my dog?
- Supports a balanced immune response to reduce overreactions to common allergens.
- Helps maintain healthy skin and reduce itching, redness and hot spots.
- Eases allergy-related discomfort by promoting a normal inflammatory response.
- Helps calm histamine reactions like sneezing, watery eyes, and irritation.
- Offers support for food sensitivities, including tummy trouble or chronic itching.
- Delivers powerful antioxidants to help protect your pup’s skin and cells from stress.
- Can be used proactively during allergy seasons to reduce the intensity of flare-ups.
How should the chews be stored?
Our chews are shelf stable and can be stored in your cupboard at room temperature for up to 3 months. If you intend to use the chews beyond 3 months, we recommend storing your chews in the fridge to preserve their freshness.
Do the chews contain any allergens?
We formulated our chews with allergies in mind. If your pet is particularly sensitive, please note that Allergy & Itch Chews includes Pork, Fish (Wild Alaskan Pollock Oil) and Brewer’s Yeast (gluten).
Can my dog overdose on these chews?
These chews are formulated with safe, well-tolerated ingredients. However, exceeding the recommended dose may cause mild digestive upset. Always follow the feeding guide and consult your vet before giving additional doses. If your pet accidentally consumes more than the recommended dose, monitor for symptoms and consult your veterinarian if concerns arise.
Where are these chews made?
Proudly made in the USA, using globally sourced ingredients.
How do I know if my dog needs an allergy supplement?
Just like us, dogs can have allergic reactions to things like pollen, dust, mold, or certain foods. If your pup deals with constant scratching, watery eyes, or skin flare-ups, adding a gentle allergy supplement to their daily routine can make a big difference. Whether your dog deals with occasional seasonal flare-ups or more regular sensitivities, this chew is designed to help them feel more comfortable – and more like themselves again.
Can these chews be used with other supplements or prescription medication?
Yes, this formula can typically be used alongside other supplements and medications. However, if your dog is on immunosuppressive therapy or has complex medical conditions, consult your veterinarian before use.
How old does my dog have to be to eat these chews?
Over 6 months of age.
Are these chews safe for cats?
These chews are specifically formulated for dogs and have not been tested for safety or efficacy in cats.
Cats have different metabolic and neurological responses to supplements, so we do not recommend giving this product to cats unless directed by a veterinarian.
Where is it made?
Our products are proudly made in the USA from globally sourced ingredients.
Do pets need joint supplements?
Joint supplements are important because they help support and maintain joint health, particularly in aging dogs or those with specific joint-related issues. They can also be beneficial for younger pups, especially larger dogs and breeds that are prone to joint issues.
Can it be used with other supplements or prescription medication?
Absolutely. As long as you follow our directions for use, our joint chews should not interfere with other supplements or prescription medications.
Where can I find my account?
All you have to do is click on the user icon on the top right of the page - right next to the shopping cart.
Where are your products made?
We’re proud to say all of our products are made in the USA with domestically and globally sourced ingredients.
How long do orders take to ship?
All orders placed before noon are shipped on the same day, while all other orders will ship within 1 business day. Not to worry, we won’t keep you waiting!
How do I return an item?
If you’re not satisfied with your purchase, please email hello@wuffes.com and our customer service will be happy to help.
Where are your products shipped from?
All our products are made in the USA and shipped from our warehouse in Denver, Colorado.
Can I give Wuffes supplements to a pregnant dog?
Our products haven’t been tested on pregnant or lactating dogs so we recommend speaking to your vet beforehand.
We’re so sure you’ll love our products, we offer a 90-day money back guarantee on all our edible supplements.
